Cancer Stem Cells


Cancer Stem Cells
Author: Rüdiger Martin Zimmerer
Publisher: Sudwestdeutscher Verlag Fur Hochschulschriften AG
ISBN: 9783838113678
Size: 78.90 MB
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Cancer Stem Cell Features In Established Melanoma Cell Lines

Cancer Stem Cells by Rüdiger Martin Zimmerer, Cancer Stem Cell Features In Established Melanoma Cell Lines Books available in PDF, EPUB, Mobi Format. Download Cancer Stem Cell Features In Established Melanoma Cell Lines books, Cancer is increasingly being viewed as a stem cell disease. According to the cancer stem cell hypothesis, tumour initiation and growth are driven by a minor subset of stem-cell-like cancer cells. These cancer stem cells (CSC) self-renew to give rise to additional CSC and differentiate to generate phenotypically diverse progeny with limited proliferative potential. CSC are capable of reconstituting tumours upon transplantation relative to bulk tumour cells or non-tumourigenic cancer cells. This model, first developed in human myeloid leukaemia, has been extended to solid tumours, such as breast and brain cancer. Most cancer stem cells were first isolated based on the expression of surface markers to distinguish CSC from cancer cells with more limited proliferative potential. CSC are usually rare in clinical specimens and hardly amenable to functional studies or to analysis of gene expression profiles. In this study a panel of melanoma cell lines was screened to identify cellular reagents sharing typical CSC features including expression of specific surface markers and genes, capacity to grow in spheroids and high clonogenic capacity.


Cancer Stem Cell Features in Established Melanoma Cell Lines
Language: en
Pages: 120
Authors: Rüdiger Martin Zimmerer
Categories:
Type: BOOK - Published: 2010-03 - Publisher: Sudwestdeutscher Verlag Fur Hochschulschriften AG
Cancer is increasingly being viewed as a stem cell disease. According to the cancer stem cell hypothesis, tumour initiation and growth are driven by a minor subset of stem-cell-like cancer cells. These cancer stem cells (CSC) self-renew to give rise to additional CSC and differentiate to generate phenotypically diverse progeny
In Vitro and in Vivo Characterization of Cancer Stem Cells in Primary Colorectal Cancer Models
Language: en
Pages: 86
Authors: Rohit Gehani
Categories: Cancer
Type: BOOK - Published: 2010 - Publisher:
Biotechnology and Bioinformatics Thesis.
Cancer Stem Cells in Lung Cancer
Language: en
Pages: 65
Authors: Koji Okudela, Hitoshi Kitamura, Noriyuki Nagahara, Akira Katayama
Categories: Medical
Type: BOOK - Published: 2011 - Publisher: Nova Biomedical Books
Of the many markers for cancer stem cells (CSCs) in lung cancer reported to date, the cell surface antigen CD133, nuclear ß-catenin accumulation, the side population phenotype, and high aldehyde dehydrogenase (ALDH) activity seem to be most reliable. This book reviews the results of studies on lung CSCs and discusses
Breast Cancer Stem Cells
Language: en
Pages:
Authors: Fengyan Yu
Categories: Medicine
Type: BOOK - Published: 2011 - Publisher:
Breast Cancer Stem Cells.
Cancer Stem Cells and Their Niche
Language: en
Pages:
Authors: Guadalupe Aparicio Gallego
Categories: Medicine
Type: BOOK - Published: 2011 - Publisher:
Cancer Stem Cells and Their Niche.
Stem Cells and Cancer Stem Cells, Volume 13
Language: en
Pages: 123
Authors: M.A. Hayat
Categories: Medical
Type: BOOK - Published: 2016-08-23 - Publisher: Springer
This is the thirteenth volume in a series which presents current understanding of stem cells and cancer stem cells. This book presents many relevant topics including the different sources of cancer stem cells: the features, roles and clinical potential of stem cells emerge from engaging with this comprehensive work. Chapters
Cancer Stem Cells CD133 Inhibition and Cytotoxicity of Certain 3-phenylthiazolo[3, 2-a]benzimidazoles: Design, Direct Synthesis, Crystal Study and in Vitro Biological Evaluation
Language: en
Pages:
Authors: M.A. Hayat
Categories: Medical
Type: BOOK - Published: 2017 - Publisher:
Books about Cancer Stem Cells CD133 Inhibition and Cytotoxicity of Certain 3-phenylthiazolo[3, 2-a]benzimidazoles: Design, Direct Synthesis, Crystal Study and in Vitro Biological Evaluation
Cytoplasmic Connexin32 and Self-Renewal of Cancer Stem Cells: Implication in Metastasis
Language: en
Pages:
Authors: Yasufumi Omori
Categories: Medicine
Type: BOOK - Published: 2012 - Publisher:
Cytoplasmic Connexin32 and Self-Renewal of Cancer Stem Cells: Implication in Metastasis.
Transcriptional Regulation of the Intestinal Cancer Stem Cell Phenotype
Language: en
Pages:
Authors: Antoine Gleizes
Categories: Medicine
Type: BOOK - Published: 2018 - Publisher:
Colorectal cancer (CRC) is one of the most frequent cancers worldwide. Current treatments include surgery and chemotherapy, but disease recurrence occurs frequently. The continuous renewal of intestinal epithelium relies on the presence of intestinal stem cells that are also at the origin of CRC and contribute to therapy resistance and
The Role of MicroRNAs in Regulating Cancer Stem Cells
Language: en
Pages:
Authors: Musaffe Tuna, Christopher I. Amos
Categories: Medicine
Type: BOOK - Published: 2011 - Publisher:
Books about The Role of MicroRNAs in Regulating Cancer Stem Cells